Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1080850 | 0.84 | PIN1 (0.47) | KDM4EKMODHODHALDH1A1PIN1 | |
| SCHEMBL15180532 | 0.83 | ALDH1A1 (0.49) | ALPLCHEK2TNKSTNKS2KDM4E | |
| SCHEMBL3094332 | 0.83 | TPMT (0.39) | CHEK2KDM4EKMOALDH1A1KMT2A | |
| SCHEMBL14952963 | 0.83 | NOTUM (0.47) | CA12ALPLRPA1CHEK2TNKS | |
| Hydrochloric Acid SCHEMBL6861539 | 0.82 | PIN1 (0.46) | KDM4EKMODHODHALDH1A1KMT2A | |
| SCHEMBL15167516 | 0.82 | GFER (0.44) | TNKSTNKS2KDM4EDHODHATM | |
| SCHEMBL724793 | 0.80 | HTT (0.41) | NR4A2BCL2L1BADTGFBR1TNKS | |
| SCHEMBL1666589 | 0.79 | ALDH1A1 (0.50) | ALPLCHEK2TNKSTNKS2LDHA | |
| SCHEMBL3367051 | 0.79 | CHEK2 (0.54) | CHEK2 | |
| SCHEMBL15967361 | 0.79 | GRK6 (0.49) | CHEK2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100540538-C | High Conductivity Calcium-Activated K Channel Opener | TANABE SEIYAKU CO (JP) | 2009-09-16 | — | — | CN | disclosed |
| CN-1503786-A | High Conductivity Calcium-Activated K Channel Opener | ������ҩ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |