Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 18/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | HTR3A | P46098 | 3/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760324 | 0.91 | HTR4 (0.52) | HTR4KCNH2HTR3A | |
| SCHEMBL2739062 | 0.89 | HTR4 (0.66) | HTR4KCNH2HTR3AHTR3EHTR3B | |
| SCHEMBL2739063 | 0.82 | HTR4 (0.64) | HTR4KCNH2HTR3AHTR3EHTR3B | |
| SCHEMBL2739064 | 0.80 | HTR4 (0.65) | HTR4KCNH2HTR3AHTR3EHTR3B | |
| SCHEMBL218594 | 0.78 | HTR4 (0.64) | HTR4KCNH2HTR3A | |
| SCHEMBL2739065 | 0.77 | HTR4 (0.61) | HTR4KCNH2HTR3AHTR3EHTR3B | |
| SCHEMBL2760323 | 0.77 | HTR4 (0.79) | HTR4KCNH2HTR3AHTR3EHTR3B | |
| SCHEMBL218595 | 0.76 | HTR4 (0.60) | HTR4KCNH2 | |
| SCHEMBL2739066 | 0.74 | HTR4 (0.60) | HTR4KCNH2HTR3AHTR3EHTR3B | |
| SCHEMBL6839835 | 0.74 | HTR4 (0.70) | HTR4KCNH2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |