SCHEMBL27604276

SCHEMBL27604276

COc1c(O)cc(F)cc1N1C=CC=NC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
DRD2 P14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28752474 0.78 CA1 (0.36)
SCHEMBL28145310 0.76 CA3 (0.40)
SCHEMBL27485237 0.69
SCHEMBL28254340 0.68
SCHEMBL17372754 0.67
SCHEMBL16043969 0.67 TDP1 (0.50) TDP1DRD2
SCHEMBL27568155 0.65 GAA (0.38) TDP1
SCHEMBL27974239 0.64
SCHEMBL27932489 0.64 TRPA1 (0.36)
SCHEMBL28261507 0.61 MAPK1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1520298-A Pyrazolopyrimidines as therapeutic agents �����ʩ���عɷݹ�˾ 2004-08-11 CN disclosed