Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896787 | 0.82 | CES2 (0.62) | KMT2ACES2CES1SMN1; SMN2PKM | |
| SCHEMBL28278771 | 0.79 | KMT2A (0.58) | KMT2ACES2CES1SMN1; SMN2PKM | |
| SCHEMBL28462172 | 0.78 | KMT2A (0.53) | KMT2ACES2CES1SMN1; SMN2PKM | |
| SCHEMBL28297982 | 0.76 | KMT2A (0.55) | KMT2ACES2CES1PKMALDH1A1 | |
| SCHEMBL584513 | 0.76 | KMT2A (0.56) | KMT2ACES2CES1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28576891 | 0.75 | KMT2A (0.50) | KMT2ACES2CES1PKMALDH1A1 | |
| SCHEMBL7073482 | 0.75 | CES1 (0.58) | KMT2ACES2CES1SMN1; SMN2PKM | |
| SCHEMBL2201261 | 0.74 | CES2 (0.62) | KMT2ACES2CES1SMN1; SMN2PKM | |
| Potassium Ion SCHEMBL28875571 | 0.74 | KMT2A (0.53) | KMT2ACES2CES1SMN1; SMN2PKM | |
| SCHEMBL28275168 | 0.74 | KMT2A (0.53) | KMT2ACES2CES1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100469778-C | Novel fused imidazole derivatives | EISAI R&D MAN CO LTD (JP) | 2009-03-18 | — | — | CN | disclosed |
| CN-100348599-C | Novel fused imidazole derivatives | EISAI CO LTD (JP) | 2007-11-14 | — | — | CN | disclosed |
| CN-1931859-A | New fused imidazole derivative | EISAI CO LTD (JP) | 2007-03-21 | — | — | CN | disclosed |
| CN-1675208-A | Novel fused imidazole derivatives | EISAI CO LTD (JP) | 2005-09-28 | — | — | CN | disclosed |