Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12419944 | 0.83 | BRD4 (0.53) | BRD4ALDH1A1HSD17B10CNR1CNR2 | |
| SCHEMBL31497570 | 0.83 | BRD4 (0.49) | BRD4ALDH1A1HSD17B10CNR1NR4A2 | |
| SCHEMBL2650431 | 0.83 | BRD4 (0.49) | BRD4ALDH1A1HSD17B10CNR1NR4A2 | |
| SCHEMBL3107925 | 0.81 | MAPK8 (0.39) | BRD4ALDH1A1HSD17B10CNR1NR4A2 | |
| SCHEMBL70381 | 0.81 | BRD4 (0.59) | BRD4ALDH1A1HSD17B10NR4A2CREBBP | |
| SCHEMBL29434198 | 0.81 | BRD4 (0.59) | BRD4ALDH1A1HSD17B10NR4A2CREBBP | |
| SCHEMBL6018021 | 0.81 | ALDH1A1 (0.47) | BRD4ALDH1A1HSD17B10CNR1NR4A2 | |
| SCHEMBL5751799 | 0.81 | LMNA (0.48) | BRD4ALDH1A1HSD17B10CNR1CNR2 | |
| SCHEMBL30874622 | 0.81 | ALDH1A1 (0.47) | BRD4ALDH1A1HSD17B10CNR1NR4A2 | |
| SCHEMBL870191 | 0.81 | ALDH1A1 (0.47) | BRD4ALDH1A1HSD17B10CNR1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100439351-C | Benzofuran derivative | TANABE SEIYAKU CO (JP) | 2008-12-03 | — | — | CN | disclosed |
| CN-1656086-A | Benzofuran derivative | TANABE SEIYAKU CO (JP) | 2005-08-17 | — | — | CN | disclosed |