Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497707 | 1.00 | CASP3 (0.62) | CASP3KMT2AMDM4TP53CASP1 | |
| SCHEMBL5497705 | 1.00 | CASP3 (0.62) | CASP3KMT2AMDM4TP53CASP1 | |
| SCHEMBL4552562 | 0.90 | CASP3 (0.71) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL13256276 | 0.90 | CASP3 (0.71) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL31498750 | 0.90 | CASP3 (0.71) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL27577211 | 0.90 | CASP3 (0.76) | CASP3KMT2ACASP1 | |
| SCHEMBL27577210 | 0.90 | CASP3 (0.76) | CASP3KMT2ACASP1 | |
| SCHEMBL30645326 | 0.85 | CASP3 (0.59) | CASP3KMT2AMDM4TP53 | |
| SCHEMBL30355286 | 0.85 | CASP3 (0.59) | CASP3KMT2AMDM4TP53 | |
| SCHEMBL30788724 | 0.84 | CASP3 (0.58) | CASP3KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1525978-A | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases | 伊邓药品公司 | 2004-09-01 | — | — | CN | disclosed |