Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 7/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577211 | 1.00 | CASP3 (0.76) | CASP3KMT2APIN1CASP1 | |
| SCHEMBL8023154 | 0.91 | CASP3 (0.68) | CASP3KMT2APIN1 | |
| SCHEMBL7404856 | 0.90 | CASP3 (0.63) | CASP3KMT2APIN1CASP1 | |
| SCHEMBL5497707 | 0.90 | CASP3 (0.62) | CASP3KMT2ACASP1 | |
| SCHEMBL27604454 | 0.90 | CASP3 (0.62) | CASP3KMT2ACASP1 | |
| SCHEMBL5497705 | 0.90 | CASP3 (0.62) | CASP3KMT2ACASP1 | |
| SCHEMBL31498750 | 0.88 | CASP3 (0.71) | CASP3KMT2A | |
| SCHEMBL4552562 | 0.88 | CASP3 (0.71) | CASP3KMT2A | |
| SCHEMBL13256276 | 0.88 | CASP3 (0.71) | CASP3KMT2A | |
| SCHEMBL8039254 | 0.87 | CASP3 (0.62) | CASP3KMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1525978-A | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases | 伊邓药品公司 | 2004-09-01 | — | — | CN | disclosed |
| CN-1313846-A | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cystenine proteases | IDUN PHARMACEUTICALS INC (US) | 2001-09-19 | — | — | CN | disclosed |