Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830285 | 0.87 | LIPG (0.48) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL22748363 | 0.84 | LIPG (0.47) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL9247277 | 0.82 | LIPG (0.49) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL29070930 | 0.80 | TLR8 (0.46) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL28757885 | 0.80 | ALOX5 (0.41) | LIPGALOX5PTGS2TAAR1BID | |
| SCHEMBL31737453 | 0.79 | BID (0.54) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL31737880 | 0.79 | LIPG (0.42) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL10349118 | 0.79 | LIPG (0.49) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL10349302 | 0.79 | LIPG (0.49) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL31737729 | 0.78 | BID (0.56) | LIPGALOX5PTGS2BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1674897-A | Phenylalkanoic acid and phenyloxyalkanoic acid derivatives as HPPAR activators | SMITHKLINE BEECHAM CORP (US) | 2005-09-28 | — | — | CN | disclosed |