Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 4/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760459 | 0.80 | MDM2 (0.36) | CTNNB1HPGDHTTALDH1A1NPC1 | |
| SCHEMBL2760475 | 0.79 | TDP1 (0.50) | HTTALDH1A1NPC1CYP3A4RAB9A | |
| SCHEMBL220492 | 0.78 | CTNNB1 (0.45) | CTNNB1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL220493 | 0.78 | CTNNB1 (0.45) | CTNNB1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL2760490 | 0.78 | POLB (0.50) | HTTNPC1RAB9ATSHR | |
| SCHEMBL2760491 | 0.77 | MDM2 (0.33) | HTTNPC1RAB9ATDP1TSHR | |
| SCHEMBL5133178 | 0.75 | CTNNB1 (0.49) | CTNNB1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL28739289 | 0.74 | CYP2C9 (0.53) | CTNNB1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL9461914 | 0.72 | CTNNB1 (0.47) | CTNNB1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL2760476 | 0.72 | NPC1 (0.44) | ALDH1A1NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | CYP2E1, CYP11B2, CYP11B1 | CTNNB1 3728/4885CYP2C9 39/4885CYP2C19 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.