SCHEMBL5133178

SCHEMBL5133178

NC(c1cccc2ccccc12)C(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.49
ALDH1A1 P00352 2/20 0.47
ACP3 P15309 4/20 0.43
CTSG P08311 1/20 0.43
CMA1 P23946 1/20 0.43
CYP2C9 P11712 3/20 0.42
CYP2C19 P33261 3/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
CYP1A2 P05177 2/20 0.42
NPC1 O15118 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
RAB9A P51151 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
METAP2 P50579 1/20 0.39
METAP1 P53582 1/20 0.39
TDP1 Q9NUW8 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461914 0.94 CTNNB1 (0.47) CTNNB1ALDH1A1ACP3CTSGCMA1
SCHEMBL28555282 0.78 CES2 (0.53) CTNNB1ALDH1A1ACP3CTSGCMA1
SCHEMBL9352212 0.77 CTNNB1 (0.51) CTNNB1ALDH1A1ACP3CTSGCMA1
SCHEMBL28739289 0.77 CYP2C9 (0.53) CTNNB1ALDH1A1ACP3CTSGCMA1
SCHEMBL4808858 0.77 CTNNB1 (0.51) CTNNB1ALDH1A1ACP3CTSGCMA1
SCHEMBL28283351 0.77 CTNNB1 (0.51) CTNNB1ALDH1A1ACP3CTSGCMA1
SCHEMBL24017144 0.76 ALDH1A1 (0.60) ALDH1A1ACP3CYP2C9CYP2C19HPGD
SCHEMBL29887508 0.76 ALDH1A1 (0.60) ALDH1A1ACP3CYP2C9CYP2C19HPGD
SCHEMBL9906119 0.76 ALDH1A1 (0.60) ALDH1A1ACP3CYP2C9CYP2C19HPGD
SCHEMBL2067587 0.76 ALDH1A1 (0.60) ALDH1A1ACP3CYP2C9CYP2C19HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1981831-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF Vaidya, Niteen A. (US) 2008-10-22 EP claimed
WO-2007092264-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2007-08-16 WO claimed