Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760727 | 1.00 | LMNA (0.41) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| SCHEMBL2760728 | 1.00 | LMNA (0.41) | LMNACYP2D6CYP2C9HSD17B10CHRM2 | |
| Mandelic Acid SCHEMBL2760729 | 0.81 | LMNA (0.40) | LMNACHRNB2CHRNB4CHRNA3CHRNA4 | |
| Mandelic Acid SCHEMBL2760726 | 0.81 | LMNA (0.40) | LMNACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7101254 | 0.79 | CYP3A4 (0.43) | CYP2C9SMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7101251 | 0.79 | CYP3A4 (0.43) | CYP2C9SMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL12102700 | 0.72 | CHRNB4 (0.41) | LMNACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2760597 | 0.72 | GRM8 (0.36) | LMNACYP2D6CYP2C9HSD17B10SMN1; SMN2 | |
| SCHEMBL16105229 | 0.70 | CHRNB4 (0.48) | LMNACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2760561 | 0.70 | CHRNB4 (0.48) | LMNACHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534667-B1 | MUSCARINIC AGONISTS | LILLY CO ELI (US) | 2010-12-15 | — | — | EP | disclosed |