Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12604444 | 0.75 | BRD4 (0.38) | HPGDTSHRBRD4GRIN2BSRD5A1 | |
| SCHEMBL6644856 | 0.70 | PSEN1 (0.42) | — | |
| SCHEMBL5764949 | 0.70 | PSEN1 (0.42) | — | |
| SCHEMBL6217567 | 0.70 | PSEN1 (0.42) | — | |
| SCHEMBL20031256 | 0.65 | BRD4 (0.46) | HPGDTSHRBRD4SRD5A1 | |
| SCHEMBL3712312 | 0.65 | DRD2 (0.47) | — | |
| SCHEMBL12232914 | 0.64 | AKR1C3 (0.43) | — | |
| SCHEMBL3713299 | 0.63 | DRD2 (0.48) | — | |
| SCHEMBL9980195 | 0.63 | BRD4 (0.38) | HPGDTSHRBRD4GRIN2BSRD5A1 | |
| SCHEMBL22287239 | 0.62 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100371336-C | Pyrrole derivatives for the treatment of cytokine mediated diseases | SANKYO CO (JP) | 2008-02-27 | — | — | CN | disclosed |
| CN-1553911-A | pyrrole derivatives, their preparation and their therapeutic use | ������������ʽ���� | 2004-12-08 | — | — | CN | disclosed |