Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673771 | 0.79 | SHBG (0.41) | SHBGALDH1A1NPSR1TSHREPHX1 | |
| SCHEMBL10899062 | 0.79 | SHBG (0.41) | SHBGALDH1A1NPSR1EPHX1TP53 | |
| SCHEMBL27321593 | 0.78 | SHBG (0.39) | SHBGNPSR1EPHX1TP53MMP2 | |
| SCHEMBL9719516 | 0.78 | SHBG (0.40) | SHBGEPHX1 | |
| SCHEMBL27998859 | 0.77 | ALDH1A1 (0.47) | SHBGALDH1A1NPSR1TSHREPHX1 | |
| SCHEMBL1357116 | 0.75 | SHBG (0.46) | SHBGALDH1A1NPSR1EPHX1TP53 | |
| SCHEMBL3751601 | 0.75 | SHBG (0.38) | SHBG | |
| SCHEMBL25251873 | 0.74 | CYP2D6 (0.44) | ALDH1A1NPSR1TSHRTHRBATM | |
| SCHEMBL18893227 | 0.74 | SHBG (0.44) | SHBGALDH1A1NPSR1TSHREPHX1 | |
| SCHEMBL1357062 | 0.74 | SHBG (0.44) | SHBGALDH1A1NPSR1TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100384842-C | 8-substituted imidazopyridines | ALTANA PHARMA AG (DE) | 2008-04-30 | — | — | CN | disclosed |
| CN-1708497-A | 8-substituted imidazopyridines | ALTANA PHARMA AG (DE) | 2005-12-14 | — | — | CN | disclosed |
| CN-1692113-A | Polysubstituted imidazopyridines as gastric secretion inhibitors | ALTANA PHARMA AG (DE) | 2005-11-02 | — | — | CN | disclosed |
| CN-1656096-A | Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders | ALTANA PHARMA AG (DE) | 2005-08-17 | — | — | CN | disclosed |
| CN-1646530-A | Nitrosated imidazopyridines | ALTANA PHARMA AG (DE) | 2005-07-27 | — | — | CN | disclosed |