Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612483 | 0.98 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL17292916 | 0.98 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6897326 | 0.94 | CA2 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL4428605 | 0.94 | CA2 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL4428606 | 0.94 | CA2 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6889610 | 0.85 | CHRM1 (0.46) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6889603 | 0.85 | CHRM1 (0.46) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7691379 | 0.83 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7686321 | 0.83 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8198245 | 0.83 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1646558-B | Histone deacetylase inhibitors and process for producing the same | KYUSHU INST TECHNOLOGY | 2010-05-12 | — | — | CN | disclosed |
| CN-1646558-A | Histone deacetylase inhibitors and methods of making the same | YOSHIDA MINORU NISHINO NORIKAZ (JP) | 2005-07-27 | — | — | CN | disclosed |