SCHEMBL27607403

SCHEMBL27607403

CCCCCOCC[Si](OCC)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.43
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 2/20 0.38
CES2 O00748 2/20 0.36
ALDH1A1 P00352 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.34
LPAR2 Q9HBW0 5/20 0.33
LPAR3 Q9UBY5 5/20 0.33
CYP3A4 P08684 1/20 0.33
CES1 P23141 1/20 0.33
LPAR6 P43657 2/20 0.33
LPAR1 Q92633 2/20 0.33
LPAR4 Q99677 2/20 0.33
LPAR5 Q9H1C0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21440327 0.93 TSHR (0.44) HTTMEN1THRBKMT2AMAPT
Propene SCHEMBL28212287 0.91 MEN1 (0.37) HTTMEN1THRBKMT2AMAPT
SCHEMBL16367157 0.88 HTT (0.50) HTTMEN1THRBKMT2AMAPT
SCHEMBL6138573 0.86
SCHEMBL28198125 0.86 HTT (0.44) HTTMEN1THRBKMT2AMAPT
SCHEMBL2581085 0.84 TSHR (0.44) HTTMEN1THRBKMT2AMAPT
SCHEMBL5158896 0.84 HSD17B10 (0.31)
SCHEMBL4688367 0.84
SCHEMBL4648090 0.84
SCHEMBL11020286 0.83 TSHR (0.43) HTTMEN1THRBKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1551908-A UV cured UV blocking compositions and methods for making and using the same �¿�ר�����޹�˾ 2004-12-01 CN disclosed