Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292156 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL27715374 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL4931059 | 0.85 | — | — | |
| Benzene SCHEMBL9467034 | 0.83 | ALDH1A1 (0.54) | TDP1TSHRALDH1A1RAB9ASMN1; SMN2 | |
| Propane SCHEMBL27631276 | 0.83 | TSHR (0.48) | TDP1TSHRALDH1A1RAB9ASMN1; SMN2 | |
| Propylene Glycol SCHEMBL8091075 | 0.81 | TDP1 (0.50) | TDP1TSHROR51E2SMN1; SMN2MAPT | |
| SCHEMBL320016 | 0.80 | — | — | |
| SCHEMBL910243 | 0.79 | TSHR (0.45) | TDP1TSHRALDH1A1RAB9ASMN1; SMN2 | |
| Nitrous Acid SCHEMBL10599928 | 0.79 | TSHR (0.45) | TDP1TSHRALDH1A1RAB9ASMN1; SMN2 | |
| Propylene Glycol SCHEMBL544720 | 0.79 | TDP1 (0.48) | TDP1TSHRALDH1A1OR51E2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102256740-A | Novel wear protection film and method for producing and using same | H C STARCK CERAMICS GMBH & CO | 2011-11-23 | — | — | CN | disclosed |
| CN-101124265-B | Aromatic polyamide porous film, process for producing the same and secondary battery | TORAY INDUSTRIES | 2011-02-02 | — | — | CN | disclosed |
| CN-100549736-C | Optical laminate, the polarization plates of using it and image display device | DAINIPPON PRINTING CO LTD (JP) | 2009-10-14 | — | — | CN | disclosed |
| CN-100524901-C | Positive electrode for lithium battery and lithium battery using the same | SHOWA DENKO KK (JP) | 2009-08-05 | — | — | CN | disclosed |
| CN-100444293-C | Method for selecting electrolyte for electric double layer capacitor | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2008-12-17 | — | — | CN | disclosed |
| CN-101163995-A | Optical multilayer body, polarizing plate using same, and image display | DAINIPPON PRINTING CO LTD (JP) | 2008-04-16 | — | — | CN | disclosed |
| CN-101124265-A | Aromatic polyamide porous film, process for producing the same and secondary battery | TORAY INDUSTRIES (JP) | 2008-02-13 | — | — | CN | disclosed |
| CN-101002350-A | Anode for lithium battery and lithium battery using the same | SHOWA DENKO KK (JP) | 2007-07-18 | — | — | CN | disclosed |
| CN-1578995-A | Method for selecting electrolyte for electric double layer capacitor | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2005-02-09 | — | — | CN | disclosed |