Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.32 |
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627889 | 0.85 | CTNNB1 (0.37) | GRM1CTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL28941788 | 0.83 | GRM1 (0.38) | GRM1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL14194550 | 0.78 | GRM5 (0.40) | CTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL4841367 | 0.76 | NPC1 (0.36) | GRM1MEN1KMT2ACTNNB1WNT3A | |
| SCHEMBL4849349 | 0.74 | USP9X (0.32) | CTNNB1WNT3A | |
| SCHEMBL14194524 | 0.71 | NSD2 (0.41) | ALDH1A1MEN1KMT2ACTNNB1WNT3A | |
| SCHEMBL17104925 | 0.69 | FFAR1 (0.53) | ALDH1A1L3MBTL1MGLLMAPK1SMN1; SMN2 | |
| SCHEMBL28756412 | 0.69 | CTNNB1 (0.40) | GRM1ALDH1A1KMT2ACTNNB1WNT3A | |
| SCHEMBL4851383 | 0.68 | ALDH1A1 (0.39) | GRM1ALDH1A1CTNNB1WNT3AKDM4E | |
| SCHEMBL4848756 | 0.65 | NPC1 (0.34) | GRM1ALDH1A1CTNNB1WNT3ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1656088-A | Substituted chroman derivatives having cytochrome P450RAI inhibitory activity | ALLERGAN INC (US) | 2005-08-17 | — | — | CN | disclosed |