SCHEMBL27609367

SCHEMBL27609367

O=C(O)Oc1ccccc1.c1ccc(-c2cccc3ccccc23)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 9/20 0.55
PPARA Q07869 9/20 0.55
CYP2C9 P11712 2/20 0.55
CYP2C19 P33261 2/20 0.55
PPARD Q03181 1/20 0.55
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
MCL1 Q07820 1/20 0.48
ACMSD Q8TDX5 1/20 0.48
CYP1A2 P05177 1/20 0.47
CHRNB2 P17787 1/20 0.47
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA4 P43681 1/20 0.47
GSK3B P49841 1/20 0.44
ADK P55263 1/20 0.44
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30356799 0.93 PPARG (0.62) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL17942333 0.93 PPARG (0.62) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL246024 0.85 PPARG (0.61) PPARGPPARACYP2C9CYP2C19PPARD
Bicarbonate SCHEMBL27850284 0.84 HDAC8 (0.61) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL238320 0.82 PPARG (0.54) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL29672358 0.81 PPARG (0.60) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL238332 0.81 PPARG (0.60) PPARGPPARACYP2C9CYP2C19PPARD
Bicarbonate SCHEMBL28016109 0.81 PPARG (0.52) PPARGPPARACYP2C9CYP2C19PPARD
Bicarbonate SCHEMBL28016107 0.81 PPARG (0.59) PPARGPPARACYP2C9CYP2C19PPARD
Bicarbonate SCHEMBL27837013 0.80 HDAC8 (0.62) PPARGPPARACYP2C9CYP2C19PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1705700-A Preparation of polycarbonates with particularly low oxygen damage BAYER MATERIALSCIENCE AG (DE) 2005-12-07 CN disclosed