Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | XDH | P47989 | 3/20 | 0.56 |
| ▸ | PDE9A | O76083 | 3/20 | 0.54 |
| ▸ | POLA1 | P09884 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269638 | 0.84 | XDH (0.56) | XDHPOLA1GDA | |
| SCHEMBL29561480 | 0.84 | XDH (0.56) | XDHPOLA1 | |
| SCHEMBL18251 | 0.84 | PNP (0.62) | XDH | |
| SCHEMBL6812718 | 0.83 | XDH (0.57) | XDHGDA | |
| SCHEMBL1394088 | 0.83 | PNP (0.61) | XDH | |
| Hydrochloric Acid SCHEMBL17186589 | 0.81 | XDH (0.53) | XDH | |
| Cyanide SCHEMBL2694132 | 0.81 | PNP (0.58) | XDH | |
| SCHEMBL1573109 | 0.80 | PDE9A (0.51) | PDE9AFABP4 | |
| SCHEMBL8145524 | 0.79 | POLA1 (0.65) | XDHPOLA1 | |
| SCHEMBL2343363 | 0.78 | XDH (0.65) | XDHGDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100379750-C | Inhibitors of nucleoside phosphorylases and nucleosidases | EINSTEIN COLL MED (US) | 2008-04-09 | — | — | CN | disclosed |
| CN-1692120-A | Nucleoside phosphorylase and nucleosidase inhibitors | EINSTEIN COLL MED (US) | 2005-11-02 | — | — | CN | disclosed |