Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.56 |
| ▸ | HTR2C | P28335 | 7/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611493 | 0.88 | HTR2C (0.58) | MCHR1HTR2CHDAC1FAAHMEN1 | |
| SCHEMBL5651954 | 0.86 | MCHR1 (0.75) | MCHR1HTR2CHDAC1 | |
| SCHEMBL27593303 | 0.84 | MCHR1 (0.56) | MCHR1HTR2CPTGDR2 | |
| SCHEMBL27611396 | 0.84 | HTR2C (0.49) | MCHR1HTR2CFAAHKMT2AALDH1A1 | |
| SCHEMBL27593236 | 0.82 | MCHR1 (0.59) | MCHR1HTR2CHDAC1MEN1KMT2A | |
| SCHEMBL27611409 | 0.80 | MCHR1 (0.60) | MCHR1HTR2CHDAC1FAAH | |
| SCHEMBL27611455 | 0.79 | MCHR1 (0.56) | MCHR1HTR2CHDAC1KMT2AALDH1A1 | |
| SCHEMBL27593277 | 0.78 | MCHR1 (0.56) | MCHR1HTR2CHDAC1 | |
| SCHEMBL27611461 | 0.77 | MCHR1 (0.47) | MCHR1HTR2CHDAC1MEN1KMT2A | |
| SCHEMBL27611419 | 0.77 | MCHR1 (0.53) | MCHR1HTR2CHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585751-A | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-02-23 | — | — | CN | disclosed |