Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.56 |
| ▸ | HTR2C | P28335 | 10/20 | 0.56 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593224 | 0.91 | MCHR1 (0.55) | MCHR1HTR2CPRSS12HDAC1GRIN1 | |
| SCHEMBL5649385 | 0.87 | MCHR1 (0.75) | MCHR1HTR2CHDAC1KCNH2 | |
| SCHEMBL27611413 | 0.84 | MCHR1 (0.58) | MCHR1HTR2CHDAC1KCNH2HDAC6 | |
| SCHEMBL28753577 | 0.83 | MCHR1 (0.59) | MCHR1HTR2C | |
| SCHEMBL5646888 | 0.79 | MCHR1 (0.73) | MCHR1HTR2CHDAC1 | |
| SCHEMBL5647195 | 0.78 | MCHR1 (0.72) | MCHR1HTR2CHDAC1 | |
| SCHEMBL27611551 | 0.77 | HTR2C (0.47) | MCHR1HTR2CTP53 | |
| SCHEMBL27611463 | 0.74 | MCHR1 (0.60) | MCHR1HTR2C | |
| SCHEMBL5651141 | 0.73 | MCHR1 (0.86) | MCHR1HTR2CHDAC1KCNH2 | |
| SCHEMBL27611409 | 0.73 | MCHR1 (0.60) | MCHR1HTR2CHDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585751-A | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-02-23 | — | — | CN | disclosed |