Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.58 |
| ▸ | HTR2C | P28335 | 7/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593236 | 0.88 | MCHR1 (0.59) | MCHR1HTR2CHDAC1HDAC6MAPT | |
| SCHEMBL27611493 | 0.88 | HTR2C (0.58) | MCHR1HTR2CHDAC1HDAC6MAPT | |
| SCHEMBL27611461 | 0.87 | MCHR1 (0.47) | MCHR1HTR2CHDAC1HDAC6MAPT | |
| SCHEMBL5644174 | 0.85 | MCHR1 (0.78) | MCHR1HTR2CHDAC1KCNH2 | |
| SCHEMBL27611533 | 0.84 | MCHR1 (0.56) | MCHR1HTR2CHDAC1HDAC6MAPT | |
| SCHEMBL27611551 | 0.82 | HTR2C (0.47) | MCHR1HTR2CKMT2AALDH1A1HTT | |
| SCHEMBL27593294 | 0.78 | MCHR1 (0.61) | MCHR1HTR2C | |
| SCHEMBL27611428 | 0.78 | MCHR1 (0.59) | MCHR1HTR2CHDAC1HDAC6TDP1 | |
| SCHEMBL27611537 | 0.77 | HTR2C (0.49) | MCHR1HTR2CMAPTMEN1KMT2A | |
| SCHEMBL27593327 | 0.77 | MCHR1 (0.59) | MCHR1HTR2CHDAC1HDAC6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585751-A | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-02-23 | — | — | CN | disclosed |