Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611396 | 0.92 | HTR2C (0.49) | HTR2CMCHR1TYK2NPC1RAB9A | |
| SCHEMBL27593236 | 0.88 | MCHR1 (0.59) | HTR2CMCHR1NPC1RAB9AGAA | |
| SCHEMBL27593397 | 0.86 | MCHR1 (0.47) | HTR2CMCHR1NPC1RAB9AGAA | |
| SCHEMBL5645913 | 0.86 | MCHR1 (0.67) | HTR2CMCHR1GAAFAAH | |
| SCHEMBL27611471 | 0.82 | MCHR1 (0.49) | HTR2CMCHR1TYK2NPC1RAB9A | |
| SCHEMBL5647100 | 0.78 | MCHR1 (0.67) | HTR2CMCHR1 | |
| SCHEMBL27611461 | 0.78 | MCHR1 (0.47) | HTR2CMCHR1NPC1RAB9AGAA | |
| SCHEMBL5644977 | 0.77 | MCHR1 (0.66) | HTR2CMCHR1GAA | |
| SCHEMBL27611493 | 0.77 | HTR2C (0.58) | HTR2CMCHR1KMT2AALDH1A1LMNA | |
| SCHEMBL27611413 | 0.77 | MCHR1 (0.58) | HTR2CMCHR1RAB9AGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585751-A | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-02-23 | — | — | CN | disclosed |