Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.59 |
| ▸ | HTR2C | P28335 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611461 | 0.89 | MCHR1 (0.47) | MCHR1HTR2CGAARAB9AALDH1A1 | |
| SCHEMBL27611537 | 0.88 | HTR2C (0.49) | MCHR1HTR2CGAARAB9AALDH1A1 | |
| SCHEMBL27611493 | 0.88 | HTR2C (0.58) | MCHR1HTR2CALDH1A1HDAC1HDAC6 | |
| SCHEMBL27611413 | 0.88 | MCHR1 (0.58) | MCHR1HTR2CGAARAB9AALDH1A1 | |
| SCHEMBL5648585 | 0.85 | MCHR1 (0.81) | MCHR1HTR2CHDAC1 | |
| SCHEMBL27611428 | 0.82 | MCHR1 (0.59) | MCHR1HTR2CGAARAB9AALDH1A1 | |
| SCHEMBL27611545 | 0.82 | MCHR1 (0.56) | MCHR1HTR2CALDH1A1HDAC1HDAC6 | |
| SCHEMBL27611396 | 0.80 | HTR2C (0.49) | MCHR1HTR2CGAARAB9AALDH1A1 | |
| SCHEMBL27593294 | 0.78 | MCHR1 (0.61) | MCHR1HTR2C | |
| SCHEMBL27593327 | 0.77 | MCHR1 (0.59) | MCHR1HTR2CHDAC1HDAC6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585751-A | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-02-23 | — | — | CN | disclosed |