Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.49 |
| ▸ | CA2 | P00918 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27849573 | 0.81 | CA1 (0.58) | CA1CA2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30613082 | 0.80 | NPC1 (0.57) | CA1CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10603799 | 0.80 | NPC1 (0.57) | CA1CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL25358934 | 0.79 | ALDH1A1 (0.53) | CA1CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5913136 | 0.78 | ALDH1A1 (0.51) | CA1CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29678316 | 0.78 | ALDH1A1 (0.51) | CA1CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1563575 | 0.78 | ALDH1A1 (0.71) | ALDH1A1HTTSMN1; SMN2LMNAMAPT | |
| SCHEMBL28787280 | 0.76 | LTC4S (0.54) | CA1CA2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5391295 | 0.74 | ALDH1A1 (0.49) | CA1CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL23972954 | 0.74 | MAPT (0.54) | CA1CA2ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1697650-B | Non-nucleoside reverse transcriptase inhibitors | ARDEA BIOSCIENCES INC | 2010-11-10 | — | — | CN | disclosed |
| CN-1697650-A | Non-nucleoside reverse transcriptase inhibitors | RIBAPHARM INC (US) | 2005-11-16 | — | — | CN | disclosed |