Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | PDXK | O00764 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | STK16 | O75716 | 1/20 | 0.35 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | OXSR1 | O95747 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612558 | 0.78 | SMN1; SMN2 (0.35) | CSNK1DMAPT | |
| SCHEMBL27631779 | 0.76 | LHCGR (0.33) | PIK3CGADORA2APIK3CDPIK3C2BPDXK | |
| SCHEMBL27612461 | 0.76 | IKBKB (0.50) | PIK3CGADORA2APIK3CDPIK3C2BPDXK | |
| SCHEMBL1116418 | 0.74 | PIK3CG (0.60) | PIK3CGADORA2APIK3CDPIK3C2BPDXK | |
| SCHEMBL27631687 | 0.73 | ADORA2A (0.45) | PIK3CGADORA2APIK3CDPIK3C2BPDXK | |
| Hydrochloric Acid SCHEMBL27631852 | 0.72 | ADORA2A (0.44) | PIK3CGADORA2APIK3CDPIK3C2BPDXK | |
| SCHEMBL27612657 | 0.72 | MAPT (0.39) | PIK3CGADORA2APIK3CDPIK3C2BPDXK | |
| SCHEMBL4411196 | 0.71 | RAB9A (0.56) | PIK3CGADORA2AADORA1ADORA2BDPP4 | |
| SCHEMBL19932545 | 0.71 | ADORA2A (0.43) | PIK3CGADORA2APIK3CDPIK3C2BPDXK | |
| SCHEMBL4419371 | 0.71 | HRH2 (0.47) | PIK3CGADORA2APIK3CDPIK3C2BPDXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |