Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653339 | 0.86 | NAPRT (0.67) | NAPRTKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL23458451 | 0.85 | NAPRT (0.59) | NAPRTKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL5046047 | 0.85 | NAPRT (0.59) | NAPRTKDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL29574424 | 0.84 | NAPRT (1.00) | NAPRTKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL28705950 | 0.84 | NAPRT (0.70) | NAPRTKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL19280924 | 0.84 | NAPRT (1.00) | NAPRTKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL229352 | 0.84 | NAPRT (1.00) | NAPRTKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL429687 | 0.83 | NAPRT (0.68) | NAPRTKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL1811012 | 0.83 | NAPRT (0.68) | NAPRTKDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL447126 | 0.83 | NAPRT (0.68) | NAPRTKDM4ETDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1571787-A | Quinuclidine derivatives processes for preparing them and their uses as M2 and/or M3 muscarinic receptor inhibitors | UCB SA (BE) | 2005-01-26 | — | — | CN | disclosed |