Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | AGER | Q15109 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | DHODH | Q02127 | 3/20 | 0.53 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229352 | 1.00 | NAPRT (1.00) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL29574424 | 1.00 | NAPRT (1.00) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL4407488 | 0.98 | NAPRT (0.96) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| Nitrous Acid SCHEMBL28824677 | 0.92 | NAPRT (0.85) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL6224044 | 0.91 | NAPRT (0.82) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| Glycine SCHEMBL29042666 | 0.89 | NAPRT (0.79) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL27791125 | 0.86 | NAPRT (0.74) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL27612856 | 0.84 | NAPRT (0.73) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL2045679 | 0.83 | NAPRT (0.71) | NAPRTKDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL28705950 | 0.83 | NAPRT (0.70) | NAPRTKDM4ETDP1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054458-B2 | 18F-tagged inhibitors of prostate specific membrane antigen (PSMA) and their use as imaging agents for prostate cancer | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2024-08-06 | — | — | US | disclosed |
| US-20240005439-A1 | IMAGING METHODS AND RADIOTRACERS FOR USE THEREIN | VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) | 2024-01-04 | — | — | US | disclosed |
| EP-4255507-A1 | IMAGING METHODS AND RADIOTRACERS FOR USE THEREIN | VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) | 2023-10-11 | — | — | EP | disclosed |
| US-20230295092-A1 | 18F - TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND THEIR USE AS IMAGING AGENTS FOR PROSTATE CANCER | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2023-09-21 | — | — | US | disclosed |
| WO-2022117714-A1 | IMAGING METHODS AND RADIOTRACERS FOR USE THEREIN | VESTLANDETS INNOVASJONS SELSKAP AS (VIS) (NO) | 2022-06-09 | — | — | WO | disclosed |
| EP-3209336-A1 | 18F-TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PROSTATE CANCER | Deutsches Krebsforschungszentrum (DE) | 2017-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12054458-B2 | 18F-tagged inhibitors of prostate specific membrane antigen (PSMA) and their use as imaging agents for prostate cancer | KLK3, FOLH1, MPI | NAPRT 1021/4885KDM4E 2235/4885TDP1 3570/4885 |
| US-20230295092-A1 | 18F - TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND THEIR USE AS IMAGING AGENTS FOR PROSTATE CANCER | KLK3, FOLH1, MPI | NAPRT 1021/4885KDM4E 2235/4885TDP1 3570/4885 |
| US-20240005439-A1 | IMAGING METHODS AND RADIOTRACERS FOR USE THEREIN | TMEM14C, GLS, ATP6V1B1 | NAPRT 1692/4885KDM4E 2723/4885TDP1 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.