Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224044 | 0.93 | NAPRT (0.82) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| SCHEMBL28705950 | 0.85 | NAPRT (0.70) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| SCHEMBL27612856 | 0.83 | NAPRT (0.73) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| SCHEMBL19280924 | 0.81 | NAPRT (1.00) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| SCHEMBL229352 | 0.81 | NAPRT (1.00) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| SCHEMBL29574424 | 0.81 | NAPRT (1.00) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| SCHEMBL447126 | 0.79 | NAPRT (0.68) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| SCHEMBL31078773 | 0.79 | NAPRT (0.68) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4407488 | 0.79 | NAPRT (0.96) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 | |
| SCHEMBL1811012 | 0.79 | NAPRT (0.68) | NAPRTALDH1A1ALOX15LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103524407-B | One group of 2-fluoro-3-pyridine carbamoyl compound | QINGDAO AGRICULTURAL UNIVERSITY (CN) | 2015-12-02 | — | — | CN | claimed |
| CN-103242308-B | 2-fluoro pyridine derivatives, as well as preparation method and application thereof | UNIV QINGDAO AGRICULTURAL | 2015-07-01 | — | — | CN | claimed |
| CN-103524407-A | 2-fluorine-3-pyridine formyl compounds | UNIV QINGDAO AGRICULTURAL | 2014-01-22 | — | — | CN | claimed |
| CN-103242308-A | 2-fluoro pyridine derivatives, as well as preparation method and application thereof | UNIV QINGDAO AGRICULTURAL | 2013-08-14 | — | — | CN | claimed |
| CN-119930720-A | Application of spinosyn derivative as pesticide | 利民化学有限责任公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-119823033-A | Synthesis method of 2-fluoropyridine-5-formyl chloride | 湖南化工研究院有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-115785180-B | Spinosyn derivative as pesticide, and preparation method and application thereof | 利民化学有限责任公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-118271285-A | Azetidine-containing amide derivative, preparation method and application thereof | 贵州大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-117510338-A | Natural naphthoquinone derivative and preparation method and application thereof | 贵州大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-116874441-A | Flexible aryl formamide derivative containing 1,2, 4-oxadiazole as well as preparation method and application thereof | 贵州大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-115785180-A | Spinosad derivative as pesticide and preparation method and application thereof | 利民化学有限责任公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-114736170-A | Aryl amide compound containing thia (oxazoline) and preparation method and application thereof in preparing bactericide | 贵州大学 | 2022-07-12 | — | — | CN | disclosed |
| US-20030203922-A1 | Substituted amine derivatives and methods of use | AMGEN INC. | 2003-10-30 | — | — | US | disclosed |
| US-20030195230-A1 | Substituted amine derivatives and methods of use | AMGEN INC. | 2003-10-16 | — | — | US | disclosed |
| US-20030134836-A1 | Substituted arylamine derivatives and methods of use | AMGEN INC. | 2003-07-17 | — | — | US | disclosed |
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AMGEN INC. | 2003-07-03 | — | — | US | disclosed |
| US-20020147198-A1 | Substituted arylamine derivatives and methods of use | AMGEN INC. | 2002-10-10 | — | — | US | disclosed |
| WO-2002068406-A2 | SUBSTITUTED AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF ANGIOGENESIS | AMGEN INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002066470-A1 | SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002055501-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMGEN INC (US) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AADAC, NAT1, PIGO | NAPRT 213/4885ALDH1A1 261/4885ALOX15 229/4885 |
| US-20030134836-A1 | Substituted arylamine derivatives and methods of use | NAT1, AADAC, AHR | NAPRT 113/4885ALDH1A1 178/4885ALOX15 588/4885 |
| US-20030203922-A1 | Substituted amine derivatives and methods of use | MAOB, HNMT, FLT4 | NAPRT 127/4885ALDH1A1 192/4885ALOX15 730/4885 |
| US-20020147198-A1 | Substituted arylamine derivatives and methods of use | NAT1, AADAC, AHR | NAPRT 113/4885ALDH1A1 178/4885ALOX15 588/4885 |
| US-20030195230-A1 | Substituted amine derivatives and methods of use | MAOB, HNMT, FLT4 | NAPRT 127/4885ALDH1A1 192/4885ALOX15 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.