Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 16/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.51 |
| ▸ | PGR | P06401 | 11/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135614 | 0.84 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL22808750 | 0.81 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5264423 | 0.79 | NR3C1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9189211 | 0.78 | CA1 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6330641 | 0.77 | NR3C1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4119631 | 0.77 | NR3C1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5664360 | 0.77 | MMP1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5663653 | 0.77 | MMP1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4120059 | 0.77 | NR3C1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27721577 | 0.77 | NR3C1 (0.58) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678306-A | -3 (sulfonamidoethyl) -indole derivaties for use as glucocorticoid mimetics in the treatment of inflammatory, allergic and proliferative diseases | BOEHRINGER INGELHEIM PHARMA (US) | 2005-10-05 | — | — | CN | disclosed |