Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612792 | 0.77 | KDM4E (0.42) | ALDH1A1LMNAKDM4EMAPTHTT | |
| SCHEMBL12899533 | 0.76 | PARP1 (0.51) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL9268910 | 0.75 | MMP2 (0.48) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL19036261 | 0.75 | HDAC6 (0.50) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL30553881 | 0.75 | KDM4E (0.59) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL3711541 | 0.75 | KDM4E (0.59) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL6189901 | 0.73 | PARP1 (0.49) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL9268906 | 0.73 | HDAC6 (0.49) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL9181528 | 0.73 | PARP1 (0.57) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL28848125 | 0.73 | KDM4E (0.54) | MMP2TSHRCHRM1COMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |