Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753662 | 0.89 | LOXL2 (0.51) | KDM4EMAPTCYP19A1ALDH1A1LMNA | |
| SCHEMBL27612934 | 0.77 | MMP2 (0.44) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL28200282 | 0.76 | MEN1 (0.50) | KDM4EMAPTGLSCYP19A1TBXAS1 | |
| SCHEMBL3136413 | 0.75 | KDM4E (0.56) | KDM4EMAPTGLSCYP19A1TBXAS1 | |
| SCHEMBL3720399 | 0.75 | KDM4E (0.59) | KDM4EMAPTGLSCYP19A1TBXAS1 | |
| SCHEMBL3783847 | 0.73 | GLS (0.49) | KDM4EMAPTGLSCYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL3712126 | 0.73 | KDM4E (0.57) | KDM4EMAPTGLSCYP19A1TBXAS1 | |
| SCHEMBL27594426 | 0.73 | MAPT (0.45) | KDM4EMAPTGLSCYP19A1TBXAS1 | |
| SCHEMBL21860417 | 0.71 | MEN1 (0.43) | KDM4EMAPTGLSCYP19A1TBXAS1 | |
| SCHEMBL27536668 | 0.70 | MAPT (0.50) | KDM4EMAPTGLSCYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |