Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 4/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761216 | 0.89 | CSGALNACT1 (0.39) | MEN1KMT2AALPLUSP2CYP3A4 | |
| SCHEMBL2635753 | 0.88 | CSGALNACT1 (0.38) | MEN1KMT2AALPLUSP2CYP3A4 | |
| SCHEMBL2761302 | 0.77 | RAB9A (0.42) | MEN1KMT2ACYP2C9 | |
| SCHEMBL2836880 | 0.77 | RAB9A (0.42) | MEN1KMT2ACYP2C9 | |
| SCHEMBL2762285 | 0.76 | SMN1; SMN2 (0.39) | KMT2AUSP2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL16700029 | 0.76 | PTGER4 (0.42) | PTGFRUSP2CYP3A4NR1I2ADRB1 | |
| SCHEMBL2839712 | 0.76 | RAB9A (0.38) | PTPN1DUSP3MAPT | |
| SCHEMBL2640655 | 0.75 | SCD (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL2761391 | 0.75 | RAB9A (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL2762295 | 0.73 | FPR2 (0.40) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141768-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |