Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612912 | 0.82 | KDM4E (0.36) | CYP19A1 | |
| SCHEMBL27594228 | 0.75 | — | — | |
| SCHEMBL27612756 | 0.71 | HDAC1 (0.31) | — | |
| SCHEMBL27613062 | 0.69 | ADRB2 (0.53) | — | |
| SCHEMBL6852712 | 0.69 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL6852705 | 0.69 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL28751296 | 0.69 | CLK4 (0.41) | CYP19A1 | |
| SCHEMBL27612769 | 0.69 | HDAC1 (0.45) | — | |
| SCHEMBL27612832 | 0.66 | AOC3 (0.37) | — | |
| SCHEMBL27612907 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |