Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850763 | 0.81 | CLK4 (0.44) | CLK4DYRK1AADRB2HCRTR1HCRTR2 | |
| SCHEMBL27613062 | 0.81 | ADRB2 (0.53) | CLK4ADRB2CYP2A6CA1CA2 | |
| SCHEMBL9796607 | 0.79 | PTGS2 (0.44) | CLK4DYRK1AADRB2HCRTR1HCRTR2 | |
| SCHEMBL2130914 | 0.77 | PRKCI (0.61) | CLK4DYRK1AADRB2HCRTR1HCRTR2 | |
| SCHEMBL27594273 | 0.74 | CLK4 (0.39) | CLK4DYRK1AADRB2HCRTR1HCRTR2 | |
| SCHEMBL27612832 | 0.73 | AOC3 (0.37) | CLK4DYRK1AADRB2KAT6A | |
| SCHEMBL112429 | 0.73 | ADRB2 (0.68) | CLK4DYRK1AADRB2CYP2A6 | |
| SCHEMBL20738473 | 0.73 | CLK4 (0.47) | CLK4DYRK1AADRB2HCRTR1HCRTR2 | |
| SCHEMBL6848165 | 0.73 | CLK4 (0.47) | CLK4DYRK1AADRB2HCRTR1HCRTR2 | |
| SCHEMBL2021727 | 0.73 | CLK4 (0.47) | CLK4DYRK1AADRB2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |