Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211866 | 0.83 | HSD11B1 (0.55) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL28041274 | 0.80 | TSHR (0.47) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL28777 | 0.79 | MLYCD (0.54) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7476159 | 0.78 | MLYCD (0.53) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL3556535 | 0.77 | TSHR (0.52) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL13479807 | 0.77 | TSHR (0.52) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL10776992 | 0.75 | TSHR (0.50) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL10841502 | 0.73 | TSHR (0.48) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL27318105 | 0.73 | TSHR (0.48) | TSHRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL27493973 | 0.73 | TSHR (0.48) | TSHRHSD11B1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |