Bromide

Bromide

SCHEMBL27613682

Br.c1ccc(C[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.43
CALM1 P0DP23 1/20 0.41
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 4/20 0.39
ALDH1A1 P00352 3/20 0.39
EPHX2 P34913 1/20 0.39
IDO1 P14902 1/20 0.38
TP53 P04637 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
TRPA1 O75762 1/20 0.38
MAOB P27338 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
CASP1 P29466 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CFTR P13569 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3188266 0.97 HPGD (0.44) HPGDCALM1CYP3A4CYP2C19MEN1
Hydrochloric Acid SCHEMBL25296192 0.95 HPGD (0.43) HPGDCALM1CYP3A4CYP2C19MEN1
Iodide SCHEMBL27594781 0.95 HPGD (0.43) HPGDCALM1CYP3A4CYP2C19MEN1
Hydrochloric Acid SCHEMBL27990626 0.95 HPGD (0.43) HPGDCALM1CYP3A4CYP2C19MEN1
SCHEMBL28404206 0.88 HPGD (0.39) HPGDCALM1CYP3A4CYP2C19MEN1
Bromide SCHEMBL29282635 0.84 ALDH1A1 (0.40) HPGDCYP3A4CYP2C19TSHRALDH1A1
Bromide SCHEMBL27281002 0.84 HTT (0.42) HPGDCYP2C19TSHRALDH1A1IDO1
Bromide SCHEMBL27276510 0.84 PLA2G1B (0.39) KMT2AALDH1A1IDO1LOXL2MAOB
SCHEMBL28471292 0.81 PLA2G1B (0.40) KMT2AALDH1A1IDO1LOXL2MAOB
SCHEMBL28122512 0.81 ALDH1A1 (0.42) HPGDCYP3A4CYP2C19TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019449-A Organic-inorganic hybrid halide perovskite material and preparation method thereof 昆明理工大学 2024-11-26 CN claimed
CN-113192716-B Soft magnetic alloy material and preparation method thereof 深圳顺络电子股份有限公司 2022-09-06 CN claimed
CN-113192716-A Soft magnetic alloy material and preparation method thereof 深圳顺络电子股份有限公司 2021-07-30 CN claimed
CN-119019449-A Organic-inorganic hybrid halide perovskite material and preparation method thereof 昆明理工大学 2024-11-26 CN disclosed
CN-118909240-A Thermoplastic resin, preparation method thereof and reinforced fiber composite material 东莞泰合复合材料有限公司 2024-11-08 CN disclosed
CN-118879306-A Zero-dimensional copper (I) -based halide flexible luminescent material and preparation method and application thereof 济宁学院 2024-11-01 CN disclosed
CN-114425430-B Catalytic cracking catalyst 中国石油化工股份有限公司 2024-03-12 CN disclosed
CN-114762831-B Preparation method and preparation system of catalytic cracking auxiliary agent 中国石油化工股份有限公司 2023-11-10 CN disclosed
CN-116917234-A Catalytic cracking agent of phosphorus-containing modified molecular sieve, preparation method and preparation system thereof, and application of catalytic cracking agent 中国石油化工股份有限公司 2023-10-20 CN disclosed
CN-114762836-B Preparation method and preparation system of catalytic cracking catalyst of phosphorus-containing modified MFI structure molecular sieve 中国石油化工股份有限公司 2023-09-05 CN disclosed
CN-114505093-B Catalytic cracking auxiliary agent and preparation method and application thereof 中国石油化工股份有限公司 2023-08-08 CN disclosed
CN-105969305-A Smart home air conditioner pipe mounting sealant 王乔 2016-09-28 CN disclosed
CN-105836825-A Sewage treatment agent 王义金 2016-08-10 CN disclosed
CN-105296241-A Anti-rust cleaning liquid for mechanical processing equipment GONG CANFENG 2016-02-03 CN disclosed
CN-105039002-A Antibacterial cleaning fluid for articles of everyday use YAO LI 2015-11-11 CN disclosed
CN-105036227-A Waste water anti-foaming agent and preparing method thereof ANHUI JIANGWEI PREC MFG CO LTD 2015-11-11 CN disclosed
CN-104177616-A Moisture-proof organic silicon material for LED encapsulation TONGLING GUOXIN LIGHT SOURCE TECHNOLOGY DEV CO LTD 2014-12-03 CN disclosed
CN-103127748-A Antifoaming agent NANTONG HAISHUN CHEMICAL CO LTD 2013-06-05 CN disclosed
CN-1615347-A Method of producing coating composition and coating composition made therefrom DU PONT (US) 2005-05-11 CN disclosed
CN-86106692-A Olefines as sterilant 1987-03-18 CN disclosed