Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27990626 | 1.00 | HPGD (0.43) | HPGDCALM1CYP3A4CYP2C19MEN1 | |
| SCHEMBL3188266 | 0.97 | HPGD (0.44) | HPGDCALM1CYP3A4CYP2C19MEN1 | |
| Bromide SCHEMBL27613682 | 0.95 | HPGD (0.43) | HPGDCALM1CYP3A4CYP2C19MEN1 | |
| Iodide SCHEMBL27594781 | 0.95 | HPGD (0.43) | HPGDCALM1CYP3A4CYP2C19MEN1 | |
| SCHEMBL28404206 | 0.88 | HPGD (0.39) | HPGDCALM1CYP3A4CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL29282636 | 0.84 | SIGMAR1 (0.42) | HPGDCYP2C19MEN1KMT2ATSHR | |
| SCHEMBL28122512 | 0.81 | ALDH1A1 (0.42) | HPGDCYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL27877085 | 0.81 | TSHR (0.54) | HPGDCYP3A4CYP2C19TSHR | |
| SCHEMBL28471292 | 0.81 | PLA2G1B (0.40) | KMT2AALDH1A1IDO1LOXL2 | |
| Bromide SCHEMBL29282635 | 0.80 | ALDH1A1 (0.40) | HPGDCYP3A4CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120059355-A | High-temperature-resistant vulcanized rubber and preparation method thereof | 江门市融泰新材料科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-116239755-B | Polyisocyanate composition with high reactivity and preparation method thereof | 万华化学集团股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119931319-A | Preparation process and application of polyurethane plastic material | 江门市新会区发达运动用品有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119409732-B | Method for preparing hexachlorocyclotriphosphazene by reaction in organic phase | 山东旭锐新材股份有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119708731-A | Tear-resistant fluororubber material and preparation method thereof | 宁波永基精密科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119677313-A | Flexible light-emitting device and preparation method thereof | 深圳大学 | 2025-03-21 | — | — | CN | claimed |
| CN-118685115-B | Fluororubber primer-free coating resistant to cold solution, preparation method and application thereof | 桂林市金谷新材料有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119590053-A | Three-layer breather valve composite diaphragm and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119590052-A | Breathing valve composite diaphragm and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119591835-A | Dual-curing type polyisocyanate composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-112831000-B | Application of PDES in bionic ion skin, bionic ion skin and preparation method and application thereof | 华南理工大学 | 2022-05-31 | — | — | CN | claimed |
| CN-114085477-A | Oil-resistant conductive fluororubber, preparation method and application | 航天材料及工艺研究所 | 2022-02-25 | — | — | CN | claimed |
| CN-113801414-A | Fluororubber with high performance retention rate at high temperature | 河北华密新材科技股份有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-113308074-A | Modified damping fluororubber for extra-high voltage single-column parallel reactor and preparation method thereof | 国网浙江省电力有限公司金华供电公司 | 2021-08-27 | — | — | CN | claimed |
| CN-109370117-B | High-flame-retardant aging-resistant fluororubber cable sheath material | 安徽中宏线缆有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-111253520-B | Polymerizable eutectic solvent for self-repairing material, conductive elastomer and preparation method | 华南理工大学 | 2021-07-02 | — | — | CN | claimed |
| CN-111087650-B | Vulcanizing agent system for fluororubber, fluororubber compound and application | 浙江加诚新材料有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-112301803-A | High-transparency conductive nano paper and convenient preparation method and application thereof | 华南理工大学 | 2021-02-02 | — | — | CN | claimed |
| CN-111087650-A | Vulcanizing agent system for fluororubber, fluororubber compound and application | 浙江加诚新材料有限公司 | 2020-05-01 | — | — | CN | claimed |
| CN-110771626-A | Efficient circulating water bactericide and preparation method thereof | 常州市振邦化工制造有限公司 | 2020-02-11 | — | — | CN | claimed |