Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.68 |
| ▸ | MMP3 | P08254 | 4/20 | 0.68 |
| ▸ | MMP13 | P45452 | 4/20 | 0.68 |
| ▸ | MMP9 | P14780 | 4/20 | 0.68 |
| ▸ | MMP1 | P03956 | 3/20 | 0.68 |
| ▸ | MMP7 | P09237 | 3/20 | 0.68 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.63 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.63 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.63 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161290 | 1.00 | MMP2 (0.68) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL2161289 | 1.00 | MMP2 (0.68) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL28216417 | 0.88 | MMP9 (0.69) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL21538660 | 0.88 | MMP9 (0.69) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL15251715 | 0.87 | SLC1A3 (0.60) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL15251716 | 0.87 | SLC1A3 (0.60) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL3187445 | 0.86 | MMP2 (0.54) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL27593856 | 0.86 | MMP2 (0.68) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL8839521 | 0.85 | MMP2 (0.91) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL6978444 | 0.85 | MMP2 (0.91) | MMP2MMP3MMP13MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1668291-A | Substituted phenylsulfonamide inhibitors of beta amyloid production | WYETH CORP (US) | 2005-09-14 | — | — | CN | disclosed |