Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27614618 | 0.82 | TTR (0.43) | MAOBMAPTNPSR1HTTLMNA | |
| SCHEMBL2914595 | 0.77 | FBP1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL27779742 | 0.75 | FBP1 (0.43) | — | |
| SCHEMBL5229776 | 0.72 | MEN1 (0.55) | MAPTCA2 | |
| SCHEMBL171651 | 0.72 | CES2 (0.67) | MAOBP2RY14CES2CES1MAP2K4 | |
| SCHEMBL5226953 | 0.70 | CYP19A1 (0.48) | MAPTHTTRAB9ALMNAPOLB | |
| Hydrochloric Acid SCHEMBL8491584 | 0.70 | CES2 (0.64) | MAOBP2RY14CES2CES1MAP2K4 | |
| Water SCHEMBL27804326 | 0.70 | CES2 (0.64) | MAOBP2RY14CES2CES1MAP2K4 | |
| Bromide SCHEMBL28812419 | 0.70 | CES2 (0.64) | MAOBP2RY14CES2CES1MAP2K4 | |
| Hydrochloric Acid SCHEMBL4376063 | 0.70 | CES2 (0.64) | MAOBP2RY14CES2CES1MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1665802-A | Bisarylsulfonamide compounds and their use in cancer therapy | CYCLACEL LTD (GB) | 2005-09-07 | — | — | CN | disclosed |