Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204875 | 0.74 | — | — | |
| SCHEMBL11781921 | 0.71 | TSHR (0.55) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL6751562 | 0.69 | — | — | |
| SCHEMBL11659865 | 0.69 | — | — | |
| SCHEMBL10499840 | 0.67 | TSHR (0.50) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL27653632 | 0.67 | — | — | |
| SCHEMBL11246445 | 0.67 | — | — | |
| SCHEMBL19508782 | 0.67 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6785363 | 0.67 | — | — | |
| SCHEMBL7784530 | 0.66 | ALDH1A1 (0.47) | TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475816-C | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2009-04-08 | — | — | CN | disclosed |
| CN-1872857-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | disclosed |
| CN-1872856-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | disclosed |
| CN-1585770-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2005-02-23 | — | — | CN | disclosed |