Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SI | P14410 | 2/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8074164 | 0.91 | — | — | |
| Methacrylic Acid SCHEMBL28537904 | 0.85 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TDP1MGAM | |
| Di(Hydroxyethyl)Ether SCHEMBL4453842 | 0.85 | ALDH1A1 (0.52) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL15334117 | 0.84 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL79590 | 0.84 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1LMNA | |
| Ethylene Glycol SCHEMBL309943 | 0.84 | — | — | |
| Ether SCHEMBL271068 | 0.82 | ALDH1A1 (0.48) | FFAR3LCKFYNALDH1A1LMNA | |
| Ether SCHEMBL151167 | 0.82 | ALDH1A1 (0.48) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetone SCHEMBL10891492 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAHSD17B10TDP1MGAM | |
| Thioglycolic Acid SCHEMBL27635363 | 0.81 | HSD17B10 (0.40) | FFAR3ALDH1A1LMNAHSD17B10PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104423700-B | Window substrate and the touch panel with the window substrate | 东友精细化工有限公司 | 2017-09-22 | — | — | CN | disclosed |
| CN-104423700-A | Window plate and touch screen panel comprising the same | DONGWOO FINE CHEM CO LTD | 2015-03-18 | — | — | CN | disclosed |
| CN-1595296-A | Lithographic antireflective hardmask compositions and uses thereof | IBM (US) | 2005-03-16 | — | — | CN | disclosed |