Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Dodecanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.50 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Docosanol SCHEMBL28032775 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Cetyl Alcohol SCHEMBL27695077 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL28593338 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL28592422 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Octacosanol SCHEMBL27695196 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL23043753 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Cetostearyl Alcohol SCHEMBL8679742 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL28887780 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL28592430 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Myristyl Alcohol SCHEMBL27916759 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114822993-B | Heat-resistant anti-aging wire harness for vehicle and preparation method thereof | 南京亿天塑料有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-114822993-A | Heat-resistant anti-aging automotive wire harness and preparation method thereof | 南京亿天塑料有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-112011413-A | Multi-surface cleaning agent containing sodium cumene sulfonate and modified surfactant | 上海毅诺生物科技有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-105193671-A | Nourishing skin care lotion and preparation method thereof | SU JIANHUA | 2015-12-30 | — | — | CN | claimed |
| CN-114822993-B | Heat-resistant anti-aging wire harness for vehicle and preparation method thereof | 南京亿天塑料有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-114822993-A | Heat-resistant anti-aging automotive wire harness and preparation method thereof | 南京亿天塑料有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-112011413-A | Multi-surface cleaning agent containing sodium cumene sulfonate and modified surfactant | 上海毅诺生物科技有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-106456516-A | Composition in the form of nano- or micro- emulsion | 莱雅公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103068786-B | Cosmetic preparation | COGNIS IP MANAGEMENT GMBH (DE) | 2016-01-20 | — | — | CN | disclosed |
| CN-105193671-A | Nourishing skin care lotion and preparation method thereof | SU JIANHUA | 2015-12-30 | — | — | CN | disclosed |
| CN-104918595-A | Cosmetic composition | OREAL | 2015-09-16 | — | — | CN | disclosed |
| CN-104902864-A | Cosmetic composition | OREAL | 2015-09-09 | — | — | CN | disclosed |
| CN-102470087-B | Ester mixtures and compositions comprising such ester mixtures | COGNIS IP MAN GMBH | 2015-07-15 | — | — | CN | disclosed |
| CN-104721072-A | Silicone (meth)acrylate Particles, Processes For Their Preparation And Use Thereof | EVONIK INDUSTRIES AG | 2015-06-24 | — | — | CN | disclosed |
| CN-104144674-A | Aqueous cosmetic composition comprising an alkylcellulose, a non-volatile oil, at least one wax and at least one gemini surfactant | OREAL | 2014-11-12 | — | — | CN | disclosed |
| CN-103282060-A | Absorbent article with lotion | PROCTER & GAMBLE | 2013-09-04 | — | — | CN | disclosed |
| CN-103068786-A | Cosmetic preparation | COGNIS IP MAN GMBH | 2013-04-24 | — | — | CN | disclosed |
| CN-101427989-A | Bioactive composition for cosmetic applications | EVONIK GOLDSCHMIDT GMBH (DE) | 2009-05-13 | — | — | CN | disclosed |
| CN-1972664-A | Antiperspirant compositions comprising ozokerite | PROCTER & GAMBLE (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1668273-A | Non-irritating antiperspirant compositions containing acidic antiperspirant active | PROCTER & GAMBLE (US) | 2005-09-14 | — | — | CN | disclosed |