Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Docosanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetyl Alcohol SCHEMBL27695077 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL28593338 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL28592422 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Octacosanol SCHEMBL27695196 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Dodecanol SCHEMBL27615232 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL23043753 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Cetostearyl Alcohol SCHEMBL8679742 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL28887780 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Citric Acid SCHEMBL28592430 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| Myristyl Alcohol SCHEMBL27916759 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072446-A | Preparation method and application of plant growth hormone | 张�林 | 2021-07-06 | — | — | CN | disclosed |
| CN-104880921-A | Image forming method | KONICA MINOLTA INC | 2015-09-02 | — | — | CN | disclosed |