Propyl Gallate

Propyl Gallate

SCHEMBL27615329

CCCOC(=O)c1cc(O)c(O)c(O)c1.O=CC(O)C(O)C(O)C(O)CO

nearest known ligand 0.52

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.52
AKR1C4 P17516 1/20 0.50
AKR1C3 P42330 1/20 0.50
AKR1C2 P52895 1/20 0.50
AKR1C1 Q04828 1/20 0.50
SERPINE1 P05121 5/20 0.49
TYR P14679 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CHRM1 P11229 1/20 0.40
TSHR P16473 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDR P35968 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propyl Gallate SCHEMBL16585562 0.91 ESR1 (0.61) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Dodecyl Gallate SCHEMBL27396926 0.91 ESR1 (0.65) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Gallic Acid Methyl Ester SCHEMBL1953233 0.85 XDH (0.55) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Demannose SCHEMBL27541194 0.83 POLB (0.39) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL3228891 0.81 SERPINE1 (0.55) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL20578289 0.81 SERPINE1 (0.55) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL1429770 0.81 ESR1 (0.65) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL3147225 0.81 ESR1 (0.65) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Gallic Acid SCHEMBL30285154 0.79 LMNA (0.50) SERPINE1L3MBTL1KDM4EPOLBALDH1A1
Gallic Acid SCHEMBL30616794 0.79 LMNA (0.50) SERPINE1L3MBTL1KDM4EPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114010597-B Propyl gallate fat emulsion injection with special grease proportion and preparation method thereof 广州白云山汉方现代药业有限公司 2023-05-16 CN disclosed
CN-114010597-A Propyl gallate fat emulsion injection with special grease proportion and preparation method thereof 广州白云山汉方现代药业有限公司 2022-02-08 CN disclosed
CN-1634589-A Injection using invert sugar water solution as carrier YANG XIHONG (CN) 2005-07-06 CN disclosed