Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615556 | 0.81 | NQO2 (0.48) | NQO2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3737543 | 0.80 | NQO2 (0.48) | NQO2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL17873521 | 0.75 | ALDH1A1 (0.45) | NQO2MEN1KMT2AALDH1A1CYP3A4 | |
| Phenol SCHEMBL27634452 | 0.73 | NQO2 (0.47) | NQO2ELANEMEN1KMT2AALDH1A1 | |
| SCHEMBL5756956 | 0.69 | NQO2 (0.50) | NQO2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5752521 | 0.67 | NQO2 (0.48) | NQO2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL13019239 | 0.67 | NQO2 (0.48) | NQO2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL8211417 | 0.66 | MEN1 (0.62) | ELANEMEN1KMT2AALDH1A1ABCG2 | |
| SCHEMBL31357879 | 0.65 | NQO2 (0.55) | NQO2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL28132957 | 0.64 | CYP19A1 (0.67) | ELANEMEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1720224-A | Vascular balancing agents and methods of use thereof | TARGEGEN INC (US) | 2006-01-11 | — | — | CN | disclosed |