Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615554 | 0.81 | NQO2 (0.44) | NQO2TDP1SMN1; SMN2LCKMAPT | |
| SCHEMBL3737543 | 0.79 | NQO2 (0.48) | NQO2TDP1SMN1; SMN2LCKMAPT | |
| SCHEMBL17873521 | 0.73 | ALDH1A1 (0.45) | NQO2TDP1ACHEHTTALDH1A1 | |
| SCHEMBL9608520 | 0.72 | KMT2A (0.49) | TDP1IKBKBSMN1; SMN2MAPTNPC1 | |
| Phenol SCHEMBL27634452 | 0.71 | NQO2 (0.47) | NQO2TDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL9608396 | 0.67 | ADORA3 (0.54) | TDP1IKBKBSMN1; SMN2MAPTNPC1 | |
| SCHEMBL5756956 | 0.67 | NQO2 (0.50) | NQO2TDP1SMN1; SMN2LCKMAPT | |
| SCHEMBL9608493 | 0.67 | MAPT (0.52) | TDP1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL13019239 | 0.65 | NQO2 (0.48) | NQO2TDP1SMN1; SMN2LCKMAPT | |
| SCHEMBL5752521 | 0.65 | NQO2 (0.48) | NQO2TDP1SMN1; SMN2LCKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1720224-A | Vascular balancing agents and methods of use thereof | TARGEGEN INC (US) | 2006-01-11 | — | — | CN | disclosed |