Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSE | P14091 | 1/20 | 0.34 |
| ▸ | PGC | P20142 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914733 | 0.81 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3ALDH1A1MAOB | |
| Tert-Butyl Formate SCHEMBL27668039 | 0.80 | CMA1 (0.35) | SLC6A4TDP1SSTR4ALDH1A1MAOB | |
| Hydrochloric Acid SCHEMBL29090963 | 0.79 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3ALDH1A1MAOB | |
| Tert-Butyl Formate SCHEMBL28024952 | 0.75 | TDP1 (0.48) | TDP1 | |
| Trifluoroacetic Acid SCHEMBL5224978 | 0.74 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3RENCYP3A4 | |
| Tert-Butyl Formate SCHEMBL27597018 | 0.73 | MGLL (0.40) | ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27993846 | 0.73 | CXCR4 (0.48) | TDP1ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28832674 | 0.72 | MAP2K1 (0.46) | SLC6A4SLC6A2SLC6A3 | |
| Tert-Butyl Formate SCHEMBL28314994 | 0.72 | TDP1 (0.48) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27744083 | 0.72 | TDP1 (0.48) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1638761-A | Azetidine derivatives as CCR-3 receptor antagonists | NOVARTIS AG (CH) | 2005-07-13 | — | — | CN | disclosed |