Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14416816 | 0.83 | THRA (0.44) | GLATHRATHRBALDH1A1MAPK1 | |
| SCHEMBL25755699 | 0.82 | HCAR2 (0.54) | ALOX15MAOAMAOB | |
| SCHEMBL21385079 | 0.81 | THRA (0.45) | GLATHRATHRBALDH1A1MAPK1 | |
| SCHEMBL111390 | 0.80 | ALDH1A1 (0.61) | SLC15A1GLAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3911621 | 0.80 | ALDH1A1 (0.45) | THRATHRBALDH1A1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL28176642 | 0.79 | ALDH1A1 (0.59) | SLC15A1GLAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6597806 | 0.79 | ALDH1A1 (0.61) | THRATHRBALDH1A1MAOAMAOB | |
| SCHEMBL27674121 | 0.79 | ALDH1A1 (0.59) | SLC15A1GLAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27801419 | 0.78 | THRA (0.40) | THRATHRBALDH1A1ADRB2ADRB1 | |
| SCHEMBL3881721 | 0.77 | THRA (0.47) | THRATHRBALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100413878-C | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2008-08-27 | — | — | CN | disclosed |
| CN-1688597-A | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2005-10-26 | — | — | CN | disclosed |