Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386606 | 0.82 | KMT2A (0.56) | SRCKMT2APDE4APDE4BPDE4C | |
| SCHEMBL10033896 | 0.81 | TSHR (0.48) | SRCKMT2AALDH1A1NPC1CYP3A4 | |
| SCHEMBL10909571 | 0.80 | KMT2A (0.58) | SRCKMT2APDE4APDE4BPDE4C | |
| SCHEMBL9304771 | 0.78 | SRC (0.57) | SRCKMT2AALDH1A1LMNACYP2C19 | |
| SCHEMBL27901034 | 0.77 | LTB4R (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL27387823 | 0.76 | SMN1; SMN2 (0.41) | KMT2AALDH1A1SMN1; SMN2CYP3A4NPSR1 | |
| SCHEMBL8993199 | 0.73 | SRC (0.52) | SRCKMT2APDE4APDE4BPDE4C | |
| SCHEMBL6677049 | 0.73 | TSHR (0.56) | SRCKMT2AALDH1A1TDP1NPC1 | |
| SCHEMBL22014067 | 0.73 | TSHR (0.56) | SRCKMT2AALDH1A1TDP1NPC1 | |
| SCHEMBL22014331 | 0.73 | TSHR (0.56) | SRCKMT2AALDH1A1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639109-A | Kinetic resolution of isomers and resolved isomers | BRISTOL MYERS SQUIBB CO (US) | 2005-07-13 | — | — | CN | disclosed |